Musculoskeletal Tumors

Pediatr Clin North Am. 2020 Feb;67(1):227-245. doi: 10.1016/j.pcl.2019.09.014.

Abstract

Pediatric musculoskeletal tumors can arise in both bone and soft tissues. The overwhelming majority of these are benign; however, rarely, malignant neoplasms do occur. These are collectively termed sarcomas, indicating their mesenchymal origin. Sarcoma management requires careful adherence to the well-described tenets of tumor management. This article summarizes the basic principles and recent advances in the management of soft tissue and bone tumors.

Keywords: Biopsy; Bone tumors; Musculoskeletal tumors; Precision medicine; Sarcoma; Soft tissue tumors; Surgical margin; Translation research.

Publication types

  • Review

MeSH terms

  • Bone Neoplasms* / diagnosis
  • Bone Neoplasms* / therapy
  • Child
  • Humans
  • Sarcoma* / diagnosis
  • Sarcoma* / therapy
  • Soft Tissue Neoplasms* / diagnosis
  • Soft Tissue Neoplasms* / therapy