Denosumab-Associated Peri-Implant Atypical Femur Fracture: A Case Report

Hawaii J Health Soc Welf. 2019 Nov;78(11 Suppl 2):47-51.

Abstract

Bisphosphonate use has been associated with atypical pathologic fracture and slowed bone turnover. We present a case of a bisphosphonate-associated peri-implant atypical femur fracture following use of a recon nail for treatment of a prior bisphosphonate-associated atypical femur fracture.

Keywords: atypical femoral fractures; bisphosphonates; denosumab; peri-implant fractures.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Bone Density Conservation Agents / adverse effects*
  • Bone Density Conservation Agents / therapeutic use
  • Bone Remodeling
  • Denosumab* / administration & dosage
  • Denosumab* / adverse effects
  • Diphosphonates* / adverse effects
  • Diphosphonates* / therapeutic use
  • Female
  • Femoral Fractures / etiology
  • Humans
  • Periprosthetic Fractures / therapy*

Substances

  • Bone Density Conservation Agents
  • Diphosphonates
  • Denosumab