Abstract
Immune reconstitution inflammatory syndrome (IRIS) represents paradoxical immune-mediated inflammation in response to an infecting pathogen, occurring after initiation of antiretroviral therapy (ART), concomitantly with immune system recovery. It has also been described in Kaposi's sarcoma (KS). We report a case of a 9-year-old Guinean girl, who developed Kaposi's sarcoma, following introduction of ART. KS associated with immune reconstitution inflammatory syndrome is rare, especially in children, but with the increased use of ART is becoming more prevalent.
Keywords:
Kaposi's sarcoma; immune reconstitution inflammatory syndrome.
© 2019 Wiley Periodicals, Inc.
MeSH terms
-
Acquired Immunodeficiency Syndrome / complications
-
Acquired Immunodeficiency Syndrome / drug therapy*
-
Anti-HIV Agents / adverse effects*
-
Anti-HIV Agents / therapeutic use*
-
Antiretroviral Therapy, Highly Active / adverse effects*
-
Child
-
Dideoxynucleosides / administration & dosage
-
Dideoxynucleosides / adverse effects
-
Drug Therapy, Combination
-
Female
-
Humans
-
Immune Reconstitution Inflammatory Syndrome / chemically induced*
-
Immune Reconstitution Inflammatory Syndrome / etiology
-
Lamivudine / administration & dosage
-
Lamivudine / adverse effects
-
Lopinavir / administration & dosage
-
Lopinavir / adverse effects
-
Ritonavir / administration & dosage
-
Ritonavir / adverse effects
-
Sarcoma, Kaposi / drug therapy*
-
Sarcoma, Kaposi / etiology
-
Sarcoma, Kaposi / pathology
Substances
-
Anti-HIV Agents
-
Dideoxynucleosides
-
Lopinavir
-
Lamivudine
-
Ritonavir
-
abacavir