Polycaprolactone as biomaterial for bone scaffolds: Review of literature

Ruby Dwivedi; Sumit Kumar; Rahul Pandey; Aman Mahajan; Deepti Nandana; Dhirendra S Katti; Divya Mehrotra

doi:10.1016/j.jobcr.2019.10.003

Polycaprolactone as biomaterial for bone scaffolds: Review of literature

J Oral Biol Craniofac Res. 2020 Jan-Mar;10(1):381-388. doi: 10.1016/j.jobcr.2019.10.003. Epub 2019 Nov 5.

Authors

Ruby Dwivedi¹, Sumit Kumar², Rahul Pandey², Aman Mahajan³, Deepti Nandana¹, Dhirendra S Katti³, Divya Mehrotra¹

Affiliations

¹ Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, KGMU, Lucknow, UP, India.
² DHR-MRU, Faculty of Dental Sciences, KGMU, Lucknow, UP, India.
³ Department of Biological Sciences and Bioengineering, IIT Kanpur, UP, India.

Abstract

Bone tissue engineering using polymer based scaffolds have been studied a lot in last decades. Considering the qualities of all the polymers desired to be used as scaffolds, Polycaprolactone (PCL) polyester apart from being biocompatible and biodegradable qualifies to an appreciable level due its easy availability, cost efficacy and suitability for modification. Its adjustable physio-chemical state, biological properties and mechanical strength renders it to withstand physical, chemical and mechanical, insults without significant loss of its properties. This review aims to critically analyse the efficacy of PCL as a biomaterial for bone scaffolds.

Keywords: Bone tissue engineering; Polycaprolactone; Scaffolds.

Publication types

Review