Treatment of Drug-Resistant Tuberculosis

Clin Chest Med. 2019 Dec;40(4):775-795. doi: 10.1016/j.ccm.2019.08.002.

Abstract

The treatment of drug-resistant tuberculosis (TB) is complicated and has evolved significantly in the past decade with the advent of rapid molecular tests and updated evidence-based guidelines of the World Health Organization and other organizations. The latest recommendations incorporate the use of new drugs and regimens that maximize efficacy and minimize toxicity to improve treatment outcomes for the patients. This article provides an overview of the latest published strategies for clinical and programmatic management of drug-resistant TB.

Keywords: Adverse drug reactions; Drug resistance; Management; Regimen; Treatment; Tuberculosis.

Publication types

  • Review

MeSH terms

  • Antitubercular Agents / therapeutic use*
  • Humans
  • Treatment Outcome
  • Tuberculosis, Multidrug-Resistant / drug therapy*
  • World Health Organization

Substances

  • Antitubercular Agents