B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

Leukemia. 2020 Apr;34(4):1158-1162. doi: 10.1038/s41375-019-0643-1. Epub 2019 Nov 12.

Alberto Bueno-Costa¹, David Piñeyro¹, Marta Soler¹, Biola M Javierre¹, Helena Raurell-Vila², Marc Subirana-Granés², Lorenzo Pasquali^{1

2

3}, Jose A Martinez-Climent^{4

5}, Manel Esteller^{6

7

8

9}

¹ Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Catalonia, Spain.
² Program of Predictive and Personalized Medicine of Cancer (PMPPC), Endocrine Regulatory Genomics Laboratory, Department of Endocrinology and Nutrition, Germans Trias i Pujol University Hospital and Research Institute (IGTP), Badalona, Catalonia, Spain.
³ CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.
⁴ Division of Hematological Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
⁵ Centro de Investigacion Biomedica en Red Cancer (CIBERONC), 28029, Madrid, Spain.
⁶ Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Catalonia, Spain. mesteller@carrerasresearch.org.
⁷ Centro de Investigacion Biomedica en Red Cancer (CIBERONC), 28029, Madrid, Spain. mesteller@carrerasresearch.org.
⁸ Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain. mesteller@carrerasresearch.org.
⁹ Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), Barcelona, Catalonia, Spain. mesteller@carrerasresearch.org.

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