Constitutional risk factors for focal neuropathies in patients referred for electromyography

Eur J Neurol. 2020 Mar;27(3):529-535. doi: 10.1111/ene.14118. Epub 2019 Nov 29.

Abstract

Background and purpose: It is well established that patient-related constitutional features predispose to focal peripheral neuropathies. Some of these risk factors were investigated in common focal neuropathies encountered in patients referred for electromyography.

Methods: Gender, age, height and body mass index (BMI) were analysed retrospectively as risk factors for 11 focal neuropathies. In all, 9686 patients (age range 18-96 years; 58% women) were included from three different centres, with identical methods and equipment.

Results: High BMI was related to carpal tunnel syndrome (CTS), ulnar neuropathy at the elbow (UNE), combined CTS and UNE, meralgia paraesthetica and lumbar radiculopathy. In women, CTS and Morton's metatarsalgia were more common, whilst long thoracic neuropathies, suprascapular neuropathies and UNE were more common in men. Older age increased the risk for CTS, UNE, Morton's metatarsalgia and radiculopathies.

Conclusions: Age, gender and BMI are important risk factors for many common focal neuropathies.

Keywords: BMI; age; constitutional factors; focal neuropathies; gender; risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Body Height
  • Body Mass Index
  • Electromyography / methods*
  • Female
  • Finland / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Peripheral Nervous System Diseases / diagnosis*
  • Peripheral Nervous System Diseases / epidemiology*
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Young Adult