Gallium scintigraphy in patients with adult T-cell leukemia lymphoma

Eur J Nucl Med. 1988;14(4):177-9. doi: 10.1007/BF00257323.

Abstract

Gallium scintigraphy was evaluated in 25 patients with adult T-cell leukemia lymphoma (ATLL). Anterior and posterior images were obtained at 72 h after administration of 3 mCi 67Ga-citrate using a gamma camera (Maxi-Camera 400 T, General Electric Co.) with a medium energy standard parallel hole collimator. Abnormally high accumulations were observed in 17 out of 25 cases (superficial lymph node, 8; hilar and mediastinal lymph node, 7; paraaortic lymph node, 2; lung, 9; liver, 1; bone, 1). There were 10 malignant lesions detected by 67Ga scintigraphy in 9 out of 17 cases (superficial lymph node, 1; hilar and mediastinal lymph node, 6; paraaortic lymph node, 1; liver, 1; bone, 1). White blood cell count and serum LDH levels were raised in patients with abnormally high accumulations of 67Ga. In conclusion, 67Ga scintigraphy seemed to be a useful examination to detect malignant lesions in patients with ATLL.

MeSH terms

  • Female
  • Gallium Radioisotopes*
  • Humans
  • Leukemia-Lymphoma, Adult T-Cell / diagnostic imaging*
  • Lung / diagnostic imaging
  • Lung Neoplasms / diagnostic imaging
  • Lymph Nodes / diagnostic imaging
  • Male
  • Middle Aged
  • Radionuclide Imaging

Substances

  • Gallium Radioisotopes