Vedolizumab use and the associations between α4β7 expression and HIV reservoir in the gut during treated primary HIV infection

AIDS. 2019 Nov 15;33(14):2268-2271. doi: 10.1097/QAD.0000000000002344.

Authors

John P Thornhill¹, Kate D Lynch, Jessica K Skelton, Marcus Dorner, Maryam Khan, Genevieve E Martin, Jonathan Hoare, Simon Peake, John Frater, Sarah Fidler

Affiliation

¹ aDivision of Medicine, Wright Fleming Institute, Imperial College, London bPeter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford cImperial College NIHR Biomedical Research Centre dNational Institute of Health Research Biomedical Research Centre eOxford NIHR Biomedical Research Centre, Oxford, UK.

PMID: 31688047
DOI: 10.1097/QAD.0000000000002344

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antibodies, Monoclonal, Humanized / therapeutic use*
CD4-Positive T-Lymphocytes / drug effects
CD4-Positive T-Lymphocytes / immunology
Crohn Disease / drug therapy
Crohn Disease / metabolism*
HIV Infections / diagnosis
HIV Infections / metabolism*
Humans
Integrins / antagonists & inhibitors
Integrins / metabolism*
Male

Substances

Antibodies, Monoclonal, Humanized
Integrins
integrin alpha4beta7
vedolizumab

Grants and funding