From palliative to curative intent: PET/CT findings in the light of breast cancer intrinsic subgroup

Tumori. 2019 Dec;105(6):NP79-NP82. doi: 10.1177/0300891619882491. Epub 2019 Oct 23.

Abstract

Purpose: Among breast cancer subgroups, Luminal A is the subgroup with the best prognosis. We report the case of a young woman presenting with a localized luminal A breast cancer with a suspicious liver lesion on initial positron emission tomography (PET)/computed tomography (CT) scan staging.

Case description: A 31-year-old woman presented with localized breast cancer accessible to curative treatment. However, PET/CT staging revealed an increase of focal activity in the liver, suspicious of a secondary malignant localization, changing the care towards palliative intent. Discrepancy between breast cancer luminal A subtype and the liver lesion led to further investigations (contrast ultrasound, magnetic resonance imaging, and biopsy), excluding a malignant process, and were in favor of toxic hepatitis, probably secondary to herbal tea consumption.

Conclusions: Questioning PET/CT findings in light of the cancer subtype enabled us to rectify the diagnosis and allow this patient to be treated with curative intent.

Keywords: Positron emission tomography/computed tomography; hepatitis; herbal tea; luminal A breast cancer; mimicking hepatic metastasis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / etiology
  • Breast Neoplasms / therapy*
  • Female
  • Humans
  • Immunohistochemistry
  • Neoplasm Staging
  • Palliative Care* / methods
  • Positron Emission Tomography Computed Tomography* / methods
  • Prognosis
  • Sensitivity and Specificity
  • Treatment Outcome