HLA-matched and HLA-haploidentical allogeneic CD19-directed chimeric antigen receptor T-cell infusions are feasible in relapsed or refractory B-cell acute lymphoblastic leukemia before hematopoietic stem cell transplantation

Leukemia. 2020 Mar;34(3):909-913. doi: 10.1038/s41375-019-0610-x. Epub 2019 Oct 18.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antigens, CD19 / immunology*
  • B-Lymphocytes / immunology
  • Female
  • HLA Antigens / immunology*
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Immunotherapy, Adoptive*
  • Leukemia, B-Cell / immunology
  • Leukemia, B-Cell / therapy*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Receptors, Chimeric Antigen / immunology
  • T-Lymphocytes / cytology
  • Treatment Outcome
  • Young Adult

Substances

  • Antigens, CD19
  • CD19 molecule, human
  • HLA Antigens
  • Receptors, Chimeric Antigen