Impact of durable ventricular assist devices on post-transplant outcomes in adults with congenital heart disease

Congenit Heart Dis. 2019 Nov;14(6):958-962. doi: 10.1111/chd.12851. Epub 2019 Oct 18.

Abstract

Background: There are no published data on post-transplant outcomes in durable ventricular assist device (VAD)-supported adult congenital heart disease (ACHD) patients.

Methods: We compared post-transplant outcomes in VAD-supported vs non-VAD-supported ACHD patients using the Scientific Registry of Transplant Recipients.

Results: At 1 year, there was no difference in post-transplant mortality between VAD-supported (12 patients) and non-VAD-supported (671 patients) ACHD patients.

Conclusions: In appropriate ACHD patients, VAD use as a bridge to transplant is a reasonable strategy.

Keywords: adult congenital heart disease; heart transplant; ventricular assist device.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Female
  • Heart Defects, Congenital / diagnosis
  • Heart Defects, Congenital / mortality
  • Heart Defects, Congenital / physiopathology
  • Heart Defects, Congenital / therapy*
  • Heart Failure / diagnosis
  • Heart Failure / mortality
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Heart Transplantation* / adverse effects
  • Heart Transplantation* / mortality
  • Heart-Assist Devices*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design
  • Prosthesis Implantation / adverse effects
  • Prosthesis Implantation / instrumentation*
  • Prosthesis Implantation / mortality
  • Registries
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • United States
  • Ventricular Function*
  • Young Adult