Potential Factors Affecting Results of Short-Type Double-Balloon Endoscope-Assisted Endoscopic Retrograde Cholangiopancreatography

Dig Dis Sci. 2020 May;65(5):1460-1470. doi: 10.1007/s10620-019-05857-3. Epub 2019 Sep 27.

Abstract

Background: Short-type double-balloon endoscope (DBE)-assisted endoscopic retrograde cholangiopancreatography (ERCP) has been developed as an alternative approach for cases with a surgically altered gastrointestinal anatomy. However, this technique is sometimes technically challenging and carries a risk of severe adverse events.

Aims: To evaluate the factors affecting the technical success rate and adverse events of DBE-ERCP.

Methods: A total of 319 patients (805 procedures) with a surgically altered gastrointestinal anatomy underwent short DBE-ERCP. The factors affecting the technical success rate and adverse events, and the learning curve of the trainees were retrospectively evaluated.

Results: The technical success rate of all procedures was 90.7%. Adverse events occurred in 44 (5.5%) procedures. A multivariate analysis indicated that Roux-en-Y reconstruction and first-time short DBE-ERCP were factors affecting the technical failure and adverse event rates, while the modified Child method after subtotal stomach-preserving pancreaticoduodenectomy reconstruction was a non-risk factor for adverse events. The trainee caseload did not affect the technical success or adverse event rates significantly; however, trainees tended to perform cases involving the modified Child method after subtotal stomach-preserving pancreaticoduodenectomy reconstruction. The success rate of scope insertion increased according to experience; however, the overall success rate did not differ to a statistically significant extent.

Conclusion: Short DBE-ERCP was useful and safe for managing cases with a surgically altered anatomy; however, trainees should concentrate on accumulating experience with easy cases, such as those with the modified Child method after subtotal stomach-preserving pancreaticoduodenectomy reconstruction or a history of DBE-ERCP.

Keywords: Biliary tract diseases; Double-balloon enteroscopy; Endoscopic retrograde cholangiopancreatography; Pancreatic diseases; Surgically altered anatomy.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Anastomosis, Roux-en-Y / adverse effects
  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects*
  • Cholangiopancreatography, Endoscopic Retrograde / instrumentation
  • Cholangiopancreatography, Endoscopic Retrograde / methods
  • Clinical Competence / statistics & numerical data*
  • Double-Balloon Enteroscopy / adverse effects*
  • Double-Balloon Enteroscopy / instrumentation
  • Double-Balloon Enteroscopy / methods
  • Endoscopes
  • Equipment Design
  • Female
  • Gastroenterologists / education
  • Gastroenterologists / statistics & numerical data*
  • Gastrointestinal Tract / abnormalities*
  • Gastrointestinal Tract / surgery
  • Humans
  • Learning Curve
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Treatment Outcome