The effectiveness and tolerability of imiquimod suppositories to treat extensive intra-anal high-grade squamous intraepithelial lesions/warts in HIV-infected individuals

Int J STD AIDS. 2019 Oct;30(12):1194-1200. doi: 10.1177/0956462419864506. Epub 2019 Sep 27.

Authors

Irene Fuertes¹, Carla Bastida², Carmen Lopez-Cabezas², Leonardo Rodríguez-Carunchio³, Jaume Ordi^{3

4}, Josep Mallolas⁵, Ross D Cranston⁵, Jose Luís Blanco⁵

Affiliations

¹ Department of Dermatology, Hospital Clinic of Barcelona, University of Barcelona, Spain.
² Department of Pharmacy, Hospital Clinic of Barcelona, University of Barcelona, Spain.
³ Department of Pathology, Hospital Clinic of Barcelona, University of Barcelona, Spain.
⁴ Institut de Salut Global de Barcelona (ISGlobal), Barcelona, Spain.
⁵ Department of Infectious Diseases, Hospital Clinic of Barcelona, University of Barcelona, Spain.

PMID: 31558130
DOI: 10.1177/0956462419864506

No abstract available

Keywords: Anal dysplasia; HIV; effectiveness; human papillomavirus; imiquimod; tolerability.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adjuvants, Immunologic / administration & dosage
Adjuvants, Immunologic / adverse effects*
Administration, Rectal
Anal Canal / pathology
Anus Neoplasms / pathology*
Anus Neoplasms / virology
Condylomata Acuminata / drug therapy*
Condylomata Acuminata / virology
Female
HIV Infections / complications*
Humans
Imiquimod / administration & dosage
Imiquimod / adverse effects*
Male
Papillomaviridae / drug effects
Papillomaviridae / isolation & purification
Papillomavirus Infections / complications
Papillomavirus Infections / drug therapy*
Papillomavirus Infections / pathology
Squamous Intraepithelial Lesions / drug therapy*
Squamous Intraepithelial Lesions / pathology
Suppositories
Treatment Outcome
Warts / drug therapy*
Warts / pathology

Substances

Adjuvants, Immunologic
Suppositories
Imiquimod