Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil

Arq Neuropsiquiatr. 2019 Sep 23;77(9):632-637. doi: 10.1590/0004-282X20190108. eCollection 2019.

Abstract

Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. OBJECTIVE This study aimed to evaluate its risk factors, outline its clinical characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis of patients with cervical arterial dissection. METHODS An observational, retrospective study using data from medical records on patients with cervical arterial dissection between January 2010 and August 2015. RESULTS The total number of patients was 41. The patients' ages ranged from 19 to 75 years, with an average of 44.5 years. The most common risk factor was smoking. Antiaggregation was used in the majority of patients (65.5%); 43% of all patients recanalized in six months, more frequently in patients who had received anticoagulation (p = 0.04). CONCLUSION The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Anticoagulants / therapeutic use
  • Atherosclerosis / etiology
  • Brazil / epidemiology
  • Carotid Artery Diseases / drug therapy
  • Carotid Artery Diseases / epidemiology
  • Carotid Artery Diseases / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Platelet Aggregation Inhibitors / therapeutic use
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Smoking / adverse effects
  • Stroke / epidemiology
  • Stroke / etiology
  • Time Factors
  • Treatment Outcome
  • Vertebral Artery Dissection / drug therapy*
  • Vertebral Artery Dissection / epidemiology
  • Vertebral Artery Dissection / etiology*
  • Young Adult

Substances

  • Anticoagulants
  • Platelet Aggregation Inhibitors