Minimal defibrillation thresholds and the correlation with implant position in subcutaneous implantable-defibrillator patients

J Cardiovasc Electrophysiol. 2019 Nov;30(11):2441-2447. doi: 10.1111/jce.14171. Epub 2019 Sep 25.

Abstract

Background: Since the introduction of the subcutaneous implantable-defibrillator (S-ICD) knowledge of factors elevating the defibrillation threshold (DFT), have increased. Optimal device positioning most likely results in a decrease in DFT. The PRAETORIAN score is a tool to systematically evaluate S-ICD implant position and predict conversion success by estimating the DFT on a chest X-ray. The objective of this study is to determine DFT in de novo S-ICD patients.

Methods: De novo S-ICD patients were enrolled with DFT testing using a single 30 J shock or a prespecified step-down protocol. Chest X-rays were obtained and implant position was evaluated using the PRAETORIAN score.

Results: Fifteen patients, age 47 (±18) years and body mass index (BMI) 25(±3) kg/m2 , underwent conversion testing with a single 30 J shock. Fourteen patients (93%) converted successfully. Implant position was optimal in all patients, PRAETORIAN score of 30 (100%). Twelve patients were available for analysis in the step-down DFT cohort, age 46 years (±15), left ventricular ejection fraction 50% (±15%) and a median BMI of 25.7 kg/m2 (range 23.8-29.1 kg/m2 ). No complications occurred during DFT testing. Mean DFT was 29 J (±12 J). Time to shock was 11 seconds (±2 seconds) for a 20 J shock compared with 17 seconds in case of a 70 J shock output. Nearly all patients were implanted with optimal device positioning with the lowest possible PRAETORIAN score of 30 (92%).

Conclusion: DFT in S-ICD patients with optimal device positioning is lower than previously reported. Conversion testing using a low shock output reduced time to therapy by 6 seconds on average.

Keywords: conversion testing; defibrillation threshold testing; implant technique; induced arrhythmias; subcutaneous ICD.

MeSH terms

  • Action Potentials
  • Adult
  • Aged
  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / physiopathology
  • Arrhythmias, Cardiac / therapy*
  • Defibrillators, Implantable*
  • Electric Countershock / adverse effects
  • Electric Countershock / instrumentation*
  • Electrophysiologic Techniques, Cardiac
  • Female
  • Heart Rate
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Prosthesis Design
  • Radiography, Thoracic
  • Time Factors
  • Treatment Outcome