Targeting neuroinflammation with brain penetrant P2X7 antagonists as novel therapeutics for neuropsychiatric disorders

Neuropsychopharmacology. 2020 Jan;45(1):234-235. doi: 10.1038/s41386-019-0502-9. Epub 2019 Sep 2.
No abstract available

Publication types

  • News
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / diagnostic imaging
  • Brain / drug effects*
  • Brain / metabolism
  • Drug Delivery Systems / methods*
  • Humans
  • Inflammation / diagnostic imaging
  • Inflammation / drug therapy
  • Inflammation / metabolism
  • Mental Disorders / diagnostic imaging
  • Mental Disorders / drug therapy*
  • Mental Disorders / metabolism
  • Nervous System Diseases / diagnostic imaging
  • Nervous System Diseases / drug therapy*
  • Nervous System Diseases / metabolism
  • Purinergic P2X Receptor Antagonists / administration & dosage*
  • Purinergic P2X Receptor Antagonists / metabolism

Substances

  • Purinergic P2X Receptor Antagonists