Successful Treatment of PAPA Syndrome with Dual Adalimumab and Tacrolimus Therapy

J Clin Immunol. 2019 Nov;39(8):832-835. doi: 10.1007/s10875-019-00685-6. Epub 2019 Aug 30.
No abstract available

Keywords: PSTPIP1-associated inflammatory diseases (PAID); Pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome; adalimumab; autoinflammatory diseases; tacrolimus.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Acne Vulgaris / diagnosis
  • Acne Vulgaris / drug therapy*
  • Acne Vulgaris / immunology
  • Adalimumab / therapeutic use*
  • Arthritis, Infectious / diagnosis
  • Arthritis, Infectious / drug therapy*
  • Arthritis, Infectious / immunology
  • Child
  • Drug Therapy, Combination / methods
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Pyoderma Gangrenosum / diagnosis
  • Pyoderma Gangrenosum / drug therapy*
  • Pyoderma Gangrenosum / immunology
  • Tacrolimus / therapeutic use*
  • Treatment Outcome

Substances

  • Immunosuppressive Agents
  • Adalimumab
  • Tacrolimus

Supplementary concepts

  • Pyogenic arthritis, pyoderma gangrenosum, and acne