1 Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK; Liverpool Heart & Chest Hospital, Liverpool, UK; Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Medical University of Silesia, Silesian Centre for Heart Diseases, Zabrze, Poland.
2 Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool L7 8TX, UK; Liverpool Heart & Chest Hospital, Liverpool, UK; Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Medical University of Silesia, Silesian Centre for Heart Diseases, Zabrze, Poland; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address: gregory.lip@liverpool.ac.uk.