Suspected Pulmonary Embolism after Oxygen-Ozone Therapy for Low Back Pain

J Neurol Surg A Cent Eur Neurosurg. 2019 Nov;80(6):503-506. doi: 10.1055/s-0039-1685197. Epub 2019 Aug 20.

Abstract

Oxygen-ozone therapy is used to treat degenerative pathology of the spine when surgery is not needed (e.g., removal of a herniated disk). Some authors have described it as a safe and effective procedure in ∼ 70 to 90% of patients. The aim of the therapy is to dehydrate the intervertebral disk and alter its contents. However, this treatment has been associated with some rare but very serious side effects. Both cardiac damage and a case of fulminant septicemia were reported. We describe a case of suspected pulmonary embolism, followed by sudden death, in an elderly woman treated with oxygen-ozone therapy for lumbar pain caused by disk protrusion. We believe a massive pulmonary embolism occurred, probably caused by an intradiskal injection that accidentally punctured a venous vessel and created emboli.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Female
  • Humans
  • Intervertebral Disc Displacement / complications
  • Intervertebral Disc Displacement / therapy*
  • Low Back Pain / etiology
  • Low Back Pain / therapy*
  • Oxygen / adverse effects*
  • Oxygen / therapeutic use
  • Ozone / adverse effects*
  • Ozone / therapeutic use
  • Pulmonary Embolism / etiology*

Substances

  • Ozone
  • Oxygen