Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development

Cell Metab. 2019 Sep 3;30(3):403-404. doi: 10.1016/j.cmet.2019.07.003. Epub 2019 Aug 1.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Glucose / metabolism
  • Carcinoma, Pancreatic Ductal / etiology*
  • Diet, High-Fat / adverse effects*
  • Disease Models, Animal
  • Female
  • Hyperinsulinism / chemically induced*
  • Hyperinsulinism / complications*
  • Insulin / genetics
  • Insulin / metabolism
  • Male
  • Mice
  • Mice, Transgenic
  • Pancreatic Neoplasms / etiology*
  • Proto-Oncogene Proteins p21(ras) / genetics

Substances

  • Blood Glucose
  • Ins1 protein, mouse
  • Ins2 protein, mouse
  • Insulin
  • Hras protein, mouse
  • Proto-Oncogene Proteins p21(ras)