Bone Health Screening Practices Among Neurologists in Patients on Antiepileptic Drugs: A Quality Improvement Project

Pediatr Neurol. 2020 Jan:102:49-55. doi: 10.1016/j.pediatrneurol.2019.06.020. Epub 2019 Jul 4.

Abstract

Background: Pediatric patients with epilepsy are at risk for low vitamin D levels, increasing the risk for bone fractures, yet standardized bone health screening is not part of routine care.

Methods: We surveyed pediatric neurologists (n = 68) at our center regarding screening practices, using an 11-item survey; constructed a bone health treatment algorithm; and developed a training intervention to improve screening rates.

Results: The overall survey response rate was 47%. Among respondents, 64% estimated that they screened for bone health less than 25% of the time. Chart review before the intervention demonstrated an overall screening rate of 25.1% (n = 50/199). One year after implementation of a standardized algorithm, the overall screening rates increased to 53.8% (n = 100/186). The frequency of prescribing vitamin D for patients treated with antiepileptic medications increased among general neurologists (preintervention rate 16%, postintervention rate 51%, P < 0.01) as well as among epileptologists (preintervention rate 45%, postintervention rate 57%, P = 0.04).

Conclusion: In a relatively short follow-up period, there were significant changes in care patterns regarding screening for bone health in pediatric patients with epilepsy. Further implementation measures are underway to increase bone health screening and care in this population.

Keywords: Bone health; Epilepsy; Quality improvement; Vitamin D.

MeSH terms

  • Adolescent
  • Anticonvulsants / adverse effects*
  • Bone Diseases / diagnosis*
  • Child
  • Drug Prescriptions / standards*
  • Drug Prescriptions / statistics & numerical data
  • Epilepsy / drug therapy*
  • Follow-Up Studies
  • Health Care Surveys
  • Hospitals, Pediatric / standards*
  • Hospitals, Pediatric / statistics & numerical data
  • Humans
  • Neurologists / standards*
  • Neurologists / statistics & numerical data
  • Pediatricians / standards*
  • Pediatricians / statistics & numerical data
  • Practice Patterns, Physicians' / standards*
  • Practice Patterns, Physicians' / statistics & numerical data
  • Quality Improvement / standards*
  • Quality Improvement / statistics & numerical data
  • Vitamin D / therapeutic use*

Substances

  • Anticonvulsants
  • Vitamin D