Disseminated toxoplasmosis associated with hemophagocytic syndrome after kidney transplantation: A case report and review

Transpl Infect Dis. 2019 Oct;21(5):e13154. doi: 10.1111/tid.13154. Epub 2019 Aug 23.

Abstract

Disseminated toxoplasmosis is infrequent after kidney transplant transmission but life-threatening because of a lack of diagnostic suspicion as well as specific chemoprophylaxis recommendations. Solid organ transplantation has resulted in few cases of disseminated toxoplasmosis presenting with associated hemophagocytic syndrome. Herein, we report, within the context of a donor/receiver mismatch, a case of a toxoplasmosis associated with hemophagocytic syndrome in a kidney transplant recipient. Molecular and serological investigations confirmed Toxoplasma gondii transmission through the kidney graft.

Keywords: hemophagocytic syndrome; renal transplant; toxoplasmosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antibodies, Protozoan / blood
  • Humans
  • Kidney / parasitology*
  • Kidney Transplantation / adverse effects*
  • Lymphohistiocytosis, Hemophagocytic / complications*
  • Male
  • Tissue Donors*
  • Toxoplasma
  • Toxoplasmosis / diagnosis*
  • Toxoplasmosis / transmission

Substances

  • Antibodies, Protozoan