Transcription Regulation: Tales of a Divergent Mediator

Xiaolu Zhao; Yifan Liu

doi:10.1016/j.cub.2019.06.033

Transcription Regulation: Tales of a Divergent Mediator

Curr Biol. 2019 Jul 22;29(14):R685-R688. doi: 10.1016/j.cub.2019.06.033.

Authors

Xiaolu Zhao¹, Yifan Liu²

Affiliations

¹ Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
² Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: yifan@med.umich.edu.

PMID: 31336084
DOI: 10.1016/j.cub.2019.06.033

Abstract

Mediator is a large, multi-module complex that plays a key role in transcription regulation in eukaryotes. A divergent Mediator from a unicellular eukaryote has been identified and characterized, revealing novel adaptations to mRNA and ncRNA transcription.

Publication types

Comment

MeSH terms

Cell Nucleus
Gene Expression Regulation
Mediator Complex*
Tetrahymena thermophila*
Transcription, Genetic

Substances

Mediator Complex