Objective: To compare biometry with new biometers of Pentacam AXL and IOLMaster 700 and the widely used biometer of IOLMaster 500 in cataract patients. Methods: Cross-sectional study. A total of 223 eyes of 147 cataract patients from Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University during 4-8 December 2017 were recruited. There were 67 males and 80 females with an age of (64±11) years.The axial length (AL), mean keratometry (Km), anterior chamber depth (ACD) and white-to-white corneal diameter (WTW) from each device were recorded. The difference and agreement between the measurements were evaluated by ANOVA, LSD test, intraclass correlation coefficient and Bland-Altman analysis. Results: The success rate of AL measurement was 85.2% (190/223) with the Pentacam AXL, 96.9% (216/223) with the IOLMaster 700 and 90.6% (202/223) with the IOLMaster 500. There was no difference among devices in measuring the AL, Km and ACD (all P>0.05). Significant difference was found in WTW [(11.36±0.42) vs. (11.69±0.45) vs. (11.45±0.42) mm; F=34.696, P=0.000]. Intraclass correlation coefficient was 0.859-1.000, and Bland-Altman analysis showed good agreement among three devices. Conclusions: The new biometers of Pentacam AXL and IOLMaster 700 and the widely used IOLMaster 500 show no difference in measuring AL, Km and ACD. All three devices show good agreement in biometry of cataract patients. (Chin J Ophthalmol, 2019, 55: 515-521).
目的： 比较两种新型生物测量仪Pentacam AXL、IOLMaster 700与IOLMaster 500对白内障患者进行眼部生物测量的差异性及一致性。 方法： 横断面研究。收集2017年12月4—8日就诊于首都医科大学附属北京同仁医院北京同仁眼科中心的白内障患者147例（223只眼），其中男性67例，女性80例；年龄（64±11）岁。分别用Pentacam AXL、IOLMaster 700与IOLMaster 500进行术前生物测量，记录参数为眼轴长度、平均角膜屈光度数、前房深度及水平角膜直径。采用方差分析及LSD-t检验比较仪器间的差异性，组内相关系数（ICC）及Bland-Altman法评价仪器的一致性。 结果： Pentacam AXL、IOLMaster 700与IOLMaster 500的眼轴检出率分别为85.2%（190/223）、96.9%（216/223）和90.6%（202/223）。方差分析显示，3种仪器测量眼轴长度、平均角膜屈光度数和前房深度差异无统计学意义（均P>0.05），Pentacam AXL、IOLMaster 700与IOLMaster 500测量的水平角膜直径分别为（11.36±0.42）、（11.69±0.45）、（11.45±0.42）mm，差异有统计学意义（F=34.696，P=0.000）。Pentacam AXL与IOLMaster 500、IOLMaster 700与IOLMaster 500、Pentacam AXL与IOLMaster 700各组测量值的ICC为0.859~1.000，Bland-Altman分析显示3种仪器测量结果一致性均较好。 结论： 新型生物测量仪Pentacam AXL、IOLMaster 700与IOLMaster 500对白内障眼的眼轴长度、平均角膜屈光度数、前房深度测量无差别，水平角膜直径测量存在一定差别，但3种仪器生物测量的一致性均较好。（中华眼科杂志，2019，55：515-521）.
Keywords: Axial length, eye; Biometry; Cataract; Refraction, ocular; Tomography, optical coherence.