Unexpected reaction patterns enable simultaneous differentiation of H2S, H2Sn and biothiols

Wenqiang Chen; Li Fu; Chunfei Chen; Junan Xiao; Wenxiu Li; Liangliang Zhang; Qi Xiao; Chusheng Huang; Jiarong Sheng; Xiangzhi Song

doi:10.1039/c9cc03054a

Unexpected reaction patterns enable simultaneous differentiation of H₂S, H₂S_n and biothiols

Chem Commun (Camb). 2019 Jul 18;55(56):8130-8133. doi: 10.1039/c9cc03054a. Epub 2019 Jun 25.

Authors

Affiliations

¹ Guangxi Key Laboratory of Natural Polymer Chemistry and Physics, Nanning Normal University, Nanning 530001, China. chenwq@csu.edu.cn shengjiarong99@163.com.
² Guangxi Zhuang Autonomous Region Environmental Monitoring Centre, Nanning, 530028, China.
³ School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China.
⁴ College of Chemistry & Chemical Engineering, Central South University, Changsha, 410083, China. xzsong@csu.edu.cn.

PMID: 31237579
DOI: 10.1039/c9cc03054a

Abstract

A robust fluorescent probe, MCP1, was developed for triple-detection of H₂S, H₂S_n and biothiols for the first time. Introduction of H₂S, H₂S_n and biothiols to MCP1 lead to distinct emission peaks at 508, 576 and 469 nm, respectively, enabling simultaneous detection of H₂S, H₂S_n and biothiols from distinct emission channels.

MeSH terms

Animals
Fluorescent Dyes / chemistry*
Hydrogen Sulfide / chemistry*
Mass Spectrometry / methods
Mice
RAW 264.7 Cells
Spectrometry, Fluorescence / methods
Spectrophotometry, Ultraviolet / methods
Sulfhydryl Compounds / chemistry*

Substances

Fluorescent Dyes
Sulfhydryl Compounds
Hydrogen Sulfide