STX11-deficient familial hemophagocytic lymphohistiocytosis type 4 is associated with self-resolving flares and a milder clinical course

Pediatr Blood Cancer. 2019 Sep;66(9):e27890. doi: 10.1002/pbc.27890. Epub 2019 Jun 17.

Authors

David E Kram¹, Michael D Santarelli², Thomas B Russell¹, Katharine B Pearsall¹, Blachy Dávila Saldaña³

Affiliations

¹ Division of Pediatric Hematology and Oncology, Wake Forest School of Medicine, Winston Salem, North Carolina.
² Department of Pediatrics, Wake Forest School of Medicine, Winston Salem, North Carolina.
³ Division of Blood and Marrow Transplantation, Children's National Medical Center, Washington, North Carolina.

PMID: 31207086
DOI: 10.1002/pbc.27890

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Humans
Infant
Lymphohistiocytosis, Hemophagocytic* / genetics
Lymphohistiocytosis, Hemophagocytic* / metabolism
Lymphohistiocytosis, Hemophagocytic* / pathology
Lymphohistiocytosis, Hemophagocytic* / physiopathology
Male
Qa-SNARE Proteins / deficiency*

Substances

Qa-SNARE Proteins
STX11 protein, human

Supplementary concepts

Hemophagocytic lymphohistiocytosis, familial, 4