'Adiós Bacteriemias': a multi-country quality improvement collaborative project to reduce the incidence of CLABSI in Latin American ICUs

Int J Qual Health Care. 2019 Nov 30;31(9):704-711. doi: 10.1093/intqhc/mzz051.

Abstract

Quality problem: The incidence of central line-associated bloodstream infections (CLABSI) in Latin America has been estimated at 4.9 episodes per 1000 central line (CL) days, compared to a pooled incidence of 0.9 in the United States. CLABSI usually result from not adhering to standardized health procedures and can be prevented using evidence-based practices.

Initial assessment: The first phase of the 'Adiós Bacteriemias' Collaborative was implemented in 39 intensive care units (ICUs) from Latin America from September 2012 to September 2013 with a 56% overall reduction in the incidence of CLABSI.

Choice of solution: Bundles of care for the processes of insertion and maintenance of CLs have proven to be effective in the reduction of CLABSI across different settings.

Implementation: Building on the results of the first phase, we implemented a second phase of the 'Adiós Bacteriemias' Collaborative between June 2014-July 2015. We adapted the Breakthrough Series (BTS) Collaborative model to guide the adoption of bundles of care for CLABSI prevention through virtual learning sessions and continuous feedback.

Evaluation: Eighty-three ICUs from five Latin American countries actively reported process and outcome measures. The overall reduction in the CLABSI incidence rate was 22% (incidence rate 0.78; 95% CI 0.65, 0.95), from 2.58 episodes per 1000 CL days at baseline to 2.02 episodes per 1000 CL days (P < 0.01) during the intervention period.

Lessons learned: Adiós Bacteriemias was effective in reducing the incidence of CLABSI and improving the adherence to good practices for CL insertion and maintenance processes in participating ICUs in Latin America.

Keywords: bundles of care; collaborative; health-care associated infections; intensive care; multi-county; quality improvement.

MeSH terms

  • Catheter-Related Infections / prevention & control*
  • Catheterization, Central Venous / methods*
  • Catheterization, Central Venous / standards
  • Central Venous Catheters / adverse effects
  • Guideline Adherence / statistics & numerical data
  • Humans
  • Infection Control / organization & administration*
  • Infection Control / standards
  • Intensive Care Units / organization & administration
  • Latin America
  • Patient Care Bundles
  • Quality Improvement / organization & administration*