High prevalence of obesity among infants presenting with intussusception: Findings in an Egyptian cohort

Arab J Gastroenterol. 2019 Jun;20(2):69-73. doi: 10.1016/j.ajg.2019.04.001. Epub 2019 May 30.

Abstract

Background and study aims: Intussusception is a life-threatening illness, with incompletely understood aetiology, although some predisposing factors are known. Intussusception frequently occurs in well-nourished chubby infants. We aimed to determine whether patients presenting with intussusception have a high prevalence of obesity.

Patients and methods: This cross sectional study was conducted in 100 infants presenting with intussusception aged ≤2 years at the Paediatric Surgery Department. Anthropometric measures, history of recent upper respiratory tract infection, timing and type of intervention were recorded. A near median split divided the population into younger (aged < 8 months, N = 47) and older (8-24 months, N = 53) groups. Obesity was defined as having a body weight for length ≥ 97.7th centile on WHO growth charts.

Results: The study comprised 58 boys and 42 girls, 31% of whom had upper respiratory infection in the preceding month. Obesity was present in 18% of patients, based on WHO growth charts. There was a trend towards higher percentage of obese infants within the younger (25%) compared to older age groups (12%, P = 0.085), but no gender difference. Obesity did not influence the rate of success of hydrostatic reduction. Based on Egypt-specific growth charts, the percentage of infants with a weight-for-age centile ≥ 85th was 42%, of whom 7% were ≥ 97.7th centile. The corresponding percentages for the weight-for-length were 29% and 15% of patients respectively.

Conclusion: There is a high prevalence of obesity in infants presenting with intussusception, particularly under 8 months of age. The mechanistic link between obesity and the pathogenesis of intussusception deserves investigation.

Keywords: Intussusception; Obesity; Weaning; Weight for age; Weight for length.

MeSH terms

  • Age Factors
  • Body Height
  • Body Weight
  • Comorbidity
  • Cross-Sectional Studies
  • Egypt / epidemiology
  • Female
  • Growth Charts
  • Humans
  • Infant
  • Intussusception / epidemiology*
  • Intussusception / therapy
  • Male
  • Obesity / epidemiology*
  • Prevalence