Three-Dimensional Evaluation and Classification of the Anatomy Variations of Vertebral Artery at the Craniovertebral Junction in 120 Patients of Basilar Invagination and Atlas Occipitalization

Oper Neurosurg (Hagerstown). 2019 Dec 1;17(6):594-602. doi: 10.1093/ons/opz076.

Abstract

Background: Patients with basilar invagination and atlas occipitalization usually present abnormal anatomy of the vertebral arteries (VAs) at the craniovertebral junction (CVJ).

Objective: To describe and further classify different types of VA variations at the CVJ with 3D visualization technology.

Methods: One hundred twenty patients with basilar invagination and atlas occipitalization who had undergone 3-dimensional computed tomographic angiography (3D-CTA) were retrospectively studied. Imaging data were processed via the separating, fusing, opacifying, and false-coloring-volume rendering technique. Abnormal anatomy of the VA at the CVJ was categorized and related anatomic parameters were measured.

Results: Seven different types were classified. Type I, VAs enter the cranium after leaving VA groove on the posterior arch of atlas (26.7% of 240 sides); Type II, VAs enter an extraosseous canal created in the assimilated atlas lateral mass-occipital condyle complex before reaching the cranium (53.3%); Type III, VA courses above the axis facet or curves below the atlas lateral mass then enter the cranium (11.7%); Type IV, VAs enter the spinal canal under the axis lamina (1.3%); Type V, high-riding VA (31.3%); Type VI, fenestrated VA (2.9%); Type VII, absent VA (4.2%). Distance from the canal of Type II VA to the posterior facet surface of atlas lateral mass (5.51 ± 2.17 mm) means a 3.5-mm screw can be safely inserted usually. Shorter distance from the midline (13.50 ± 4.35) illustrates potential Type III VA injury during exposure. Decreased height and width of axis isthmus in Type V indicate increased VA injury risks.

Conclusion: Seven types of VA variations were described, together with valuable information helpful to minimize VA injury risk intraoperatively.

Keywords: Basilar invagination and atlas occipitalization; Classification; SFOF-VR technology; Vertebral artery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Central Nervous System Vascular Malformations / classification
  • Central Nervous System Vascular Malformations / complications
  • Central Nervous System Vascular Malformations / diagnostic imaging*
  • Cerebral Angiography
  • Cervical Atlas / abnormalities*
  • Child
  • Computed Tomography Angiography
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Male
  • Middle Aged
  • Musculoskeletal Abnormalities / complications
  • Occipital Bone / abnormalities*
  • Platybasia / diagnostic imaging*
  • Retrospective Studies
  • Vertebral Artery / abnormalities
  • Vertebral Artery / diagnostic imaging*
  • Young Adult