Abstract
In an open trial, five of eight panic disorder patients and none of five control subjects panicked after inhalation of two breaths of 35% CO2 and 65% O2; none panicked after placebo. Using 35% CO2 to induce panic is safe, simple, and well tolerated and may provide a valuable laboratory model of panic.
Publication types
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Clinical Trial
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Controlled Clinical Trial
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Administration, Inhalation
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Adult
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Anxiety Disorders / chemically induced*
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Anxiety Disorders / diagnosis
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Carbon Dioxide* / administration & dosage
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Fear*
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Humans
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Oxygen / administration & dosage
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Panic*
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Pilot Projects