First detection of the mcr-1 colistin resistance gene in Escherichia coli from a patient with urinary tract infection in Myanmar

New Microbes New Infect. 2019 Apr 10:30:100550. doi: 10.1016/j.nmni.2019.100550. eCollection 2019 Jul.

Abstract

Colistin-resistance gene mcr-1 was detected in an Escherichia coli sample among 442 clinical isolates collected in a tertiary-care hospital in Yangon, Myanmar, in 2018. This isolate was classified into phylogroup A-ST23 complex and harboured bla CTX-M-15 and bla TEM-1, associated with multiple mutations in quinolone-resistance-determining regions in gyrA and parC.

Keywords: Escherichia coli; Myanmar; ST23 complex; colistin resistance; mcr-1.