Next generation sequencing redefines a triple negative essential thrombocythaemia as double-positive with rare mutations on JAK2 V617 and MPL W515 hotspots

Br J Haematol. 2019 Sep;186(5):785-788. doi: 10.1111/bjh.15954. Epub 2019 May 14.
No abstract available

Keywords: essential thrombocythaemia; molecular biology; molecular haematology; myeloproliferative disease; next generation sequencing.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Female
  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Janus Kinase 2 / genetics*
  • Mutation
  • Receptors, Thrombopoietin / genetics*
  • Thrombocythemia, Essential / genetics*

Substances

  • Receptors, Thrombopoietin
  • MPL protein, human
  • Janus Kinase 2