Pattern and Outcome of Uveitis in a Tertiary Military Hospital in Thailand

Ocul Immunol Inflamm. 2020 Apr 2;28(3):424-432. doi: 10.1080/09273948.2019.1589527. Epub 2019 Apr 22.

Abstract

Background: Causes of uveitis vary upon the epidemiologic, racial, and geographical variations.

Objective: The objective of the study is to analyze pattern and outcome of uveitis in Phramongkutklao Hospital.

Methods: This is a retrospective study.

Results: Rate of uveitis was 580 cases per 100 000 persons including infectious uveitis (20%), idiopathic (36%), and noninfectious (44%). The male-to-female ratio was 1.2:1. Anterior uveitis was the most common (50%) followed by panuveitis (25.6%), posterior uveitis (12.3%), and intermediate uveitis (7.3%). The three most common causes were Behçet's disease, HLA-B27-associated uveitis, and herpetic iridocyclitis. A total of 62 patients (10.6%) suffered from blindness, for which the most diagnostic disease was Behçet's disease. The most common complication was glaucoma (21%). Acute onset, unilateral, posterior uveitis, granulomatous inflammation, and complications differed significantly between the infectious and noninfectious groups (p < 0.001).

Conclusion: The rate of uveitis was 0.58% and noninfectious uveitis was common. Clinical presentations regarding acute onset, unilateral, posterior uveitis, and granulomatous inflammation suggest infectious causes.

Keywords: Thailand; infection; outcome; pattern; uveitis.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Child
  • Cross-Sectional Studies
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Hospitals, Military / statistics & numerical data*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Severity of Illness Index
  • Tertiary Care Centers / statistics & numerical data*
  • Thailand / epidemiology
  • Tomography, Optical Coherence
  • Uveitis / diagnosis
  • Uveitis / epidemiology*
  • Young Adult