Methicillin-Resistant Staphylococcus aureus Harboring mecC Still Eludes Us in East London, United Kingdom

J Clin Microbiol. 2019 May 24;57(6):e00020-19. doi: 10.1128/JCM.00020-19. Print 2019 Jun.

Abstract

Reports of methicillin-resistant Staphylococcus aureus (MRSA) harboring the mecC gene have increased in the UK since first being described. To our diagnostic S. aureus multiplex PCR, a mecC primer set was designed and implemented, and then the prevalence in our patient population was investigated. Fewer than 1% of the clinical isolates possessed the mecC gene, confirming that mecA remains the dominant genetic determinant of MRSA in East London.

Keywords: MRSA; PCR; mecC.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Bacterial Proteins / genetics*
  • Child
  • Child, Preschool
  • Female
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • London / epidemiology
  • Male
  • Methicillin-Resistant Staphylococcus aureus / classification
  • Methicillin-Resistant Staphylococcus aureus / genetics*
  • Middle Aged
  • Multiplex Polymerase Chain Reaction
  • Prevalence
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology*
  • Young Adult

Substances

  • Bacterial Proteins