Enduring efficacy and tolerability of daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma (GEN503): final results of an open-label, phase 1/2 study

Br J Haematol. 2019 Aug;186(3):e35-e39. doi: 10.1111/bjh.15879. Epub 2019 Mar 31.
No abstract available

Keywords: daratumumab; monoclonal antibody; multiple myeloma; plasma cell disorders; relapsed/refractory multiple myeloma.

Publication types

  • Clinical Trial, Phase I
  • Clinical Trial, Phase II
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiogenesis Inhibitors / administration & dosage
  • Angiogenesis Inhibitors / adverse effects
  • Antibodies, Monoclonal / administration & dosage
  • Antibodies, Monoclonal / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Dexamethasone / administration & dosage
  • Dexamethasone / adverse effects
  • Female
  • Humans
  • Lenalidomide / administration & dosage
  • Lenalidomide / adverse effects
  • Male
  • Multiple Myeloma / drug therapy*
  • Neoplasm Recurrence, Local
  • Progression-Free Survival

Substances

  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal
  • daratumumab
  • Dexamethasone
  • Lenalidomide