Invasive Group A Streptococcus Infection in Children in Southern Israel Before and After the Introduction of Varicella Vaccine

J Pediatric Infect Dis Soc. 2020 Apr 30;9(2):236-239. doi: 10.1093/jpids/piz013.

Abstract

The annual rates of group A Streptococcus bacteremia per 100 000 children in southern Israel declined after introduction of the varicella vaccine to the national immunization program, from 2.43 (95% confidence interval, 1.73-3.13) in 1995-2002 to 1.30 (95% confidence interval, 0.91-1.72) in 2010-2016 (P = .04). This reduction correlated with the disappearance of varicella rash as a predisposing factor.

Keywords: emm type; invasive group A Streptococcus; varicella vaccine.

MeSH terms

  • Bacteremia / epidemiology
  • Chickenpox / complications*
  • Chickenpox / prevention & control
  • Chickenpox Vaccine*
  • Child, Preschool
  • Drug Resistance, Bacterial
  • Exanthema / complications
  • Exanthema / epidemiology
  • Female
  • Humans
  • Infant
  • Israel / epidemiology
  • Male
  • Streptococcal Infections / epidemiology*
  • Streptococcal Infections / etiology
  • Streptococcus pyogenes*

Substances

  • Chickenpox Vaccine