We present a case series describing a unique entity as it relates to plateau iris. There have been many established risk factors for plateau iris, but we present the following cases that describe patients with plateau iris in the setting of prematurity and/or retinopathy of prematurity as well as high myopia or emmetropia. We believe this to be a distinct form of plateau iris resulting from abnormal ciliary body and angle development in the preterm infant. Subjects were treated according to standard of care, with laser peripheral iridotomies, laser iridoplasty, and even glaucoma drainage implants, as indicated.