The Long and the Short of the RNA Polymerase C-Terminal Domain and Phase Separation

R Stefan Isaac; L Stirling Churchman

doi:10.1016/j.molcel.2019.03.004

The Long and the Short of the RNA Polymerase C-Terminal Domain and Phase Separation

Mol Cell. 2019 Mar 21;73(6):1087-1088. doi: 10.1016/j.molcel.2019.03.004.

Authors

R Stefan Isaac¹, L Stirling Churchman²

Affiliations

¹ Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
² Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: churchman@genetics.med.harvard.edu.

PMID: 30901560
DOI: 10.1016/j.molcel.2019.03.004

Abstract

In this issue of Molecular Cell, Lu et al. (2019) analyze the role of the length and sequence complexity of the RNA polymerase II unstructured C-terminal domain in animal viability, development, and the dynamics of RNA polymerase II in vivo.

Publication types

Comment

MeSH terms

Animals
Consensus
Drosophila
RNA Polymerase II*
RNA Polymerase III*

Substances

RNA Polymerase II
RNA Polymerase III