Efficacy and risk profile of self-expandable stents in the management of pediatric esophageal pathology

J Pediatr Surg. 2019 Jun;54(6):1233-1238. doi: 10.1016/j.jpedsurg.2019.02.025. Epub 2019 Feb 28.

Abstract

Purpose: The purpose of this study was to evaluate the efficacy and risk profile of esophageal stents in the management of complicated pediatric esophageal disease.

Methods: An IRB-approved, single-center, retrospective review was performed on all pediatric patients (n = 13) who underwent esophageal stent placement (2005-2017). Demographic, perioperative, and outcome data were analyzed (p < 0.05).

Results: Forty-one stents were placed due to recalcitrant strictures (n = 36), perforations (n = 2), and/or fistulae (n = 3). Median age at initial stent placement was 23.8 months (range, 50 days to 16 years), and median stent duration was 36 days (range, 3-335). The recurrence rate for strictures after initial stent removal was 100%. Four (31%) children subsequently underwent definitive operative repair. There were 5 deaths, including 2 related to stent placement. Seventy-one percent of stents were associated with an adverse event, most commonly intraluminal migration (56%). Younger children experienced an increased risk for airway compression and retching (p = 0.010).

Conclusion: These data suggest that stents are associated with high complication rates and are not effective as definitive therapy for recalcitrant strictures in children. Although there may be a temporizing role for stents in selected patients, further refinements in stent technologies are needed to help manage this difficult patient population.

Level of evidence: Level IV.

Keywords: Esophageal atresia; Stents; Strictures; Tracheoesophageal fistula.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Digestive System Surgical Procedures* / adverse effects
  • Digestive System Surgical Procedures* / instrumentation
  • Digestive System Surgical Procedures* / methods
  • Digestive System Surgical Procedures* / statistics & numerical data
  • Esophageal Diseases* / epidemiology
  • Esophageal Diseases* / surgery
  • Humans
  • Infant
  • Retrospective Studies
  • Stents* / adverse effects
  • Stents* / statistics & numerical data