The role of cardiac imaging in the management of non-ischemic cardiovascular diseases in human immunodeficiency virus infection

J Nucl Cardiol. 2020 Jun;27(3):801-818. doi: 10.1007/s12350-019-01676-1. Epub 2019 Mar 12.

Abstract

Infection with human immunodeficiency virus (HIV) has become the pandemic of the new century. About 36.9 million people are living with HIV worldwide. The introduction of antiretroviral therapy in 1996 has dramatically changed the global landscape of HIV care, resulting in significantly improved survival and changing HIV to a chronic disease. With near-normal life expectancy, contemporary cardiac care faces multiple challenges of cardiovascular diseases, disorders specific to HIV/AIDS, and those related to aging and higher prevalence of traditional risk factors. Non-ischemic cardiovascular diseases are major components of cardiovascular morbidity and mortality in HIV/AIDS. Non-invasive cardiac imaging plays a pivotal role in the management of these diseases. This review summarizes the non-ischemic presentation of the HIV cardiovascular spectrum focusing on the role of cardiac imaging in the management of these disorders.

Keywords: Cardiomyopathy; endocarditis; heart failure; human immunodeficiency virus; pericarditis; vasculitis.

MeSH terms

  • Anti-Retroviral Agents / therapeutic use*
  • Aortitis / complications
  • Aortitis / diagnostic imaging
  • Arrhythmias, Cardiac / complications
  • Arrhythmias, Cardiac / diagnostic imaging
  • Cardiovascular Diseases / complications
  • Cardiovascular Diseases / diagnostic imaging*
  • Death, Sudden, Cardiac
  • Female
  • HIV Infections / complications
  • HIV Infections / diagnostic imaging*
  • Heart Neoplasms / complications
  • Heart Neoplasms / diagnostic imaging
  • Humans
  • Male
  • Middle Aged
  • Myocardial Perfusion Imaging / methods
  • Pericardium / pathology
  • Prognosis
  • Risk Factors
  • Vascular Diseases / complications
  • Vascular Diseases / diagnostic imaging

Substances

  • Anti-Retroviral Agents