Maturity-onset diabetes of the young type 5 uncovered during pregnancy with a long-term diagnosis of type 1 diabetes

J Diabetes Investig. 2019 Nov;10(6):1590-1592. doi: 10.1111/jdi.13036. Epub 2019 Apr 2.

Abstract

We report a case of missed diagnosis of maturity-onset diabetes of the young type 5 uncovered during pregnancy with a previous diagnosis of type 1 diabetes. Maturity-onset diabetes of the young type 5 cannot be excluded in early-onset diabetes with positive islet-related autoantibodies and type 1 diabetes-prone human leukocyte antigen subtypes. Abdominal ultrasound should be used in all patients with pre-gestational diabetes, and maturity-onset diabetes of the young type 5 should be considered when renal abnormality is presented.

Keywords: Abdominal ultrasound; Glutamic acid decarboxylase antibody; Maturity-onset diabetes of the young type 5 during pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoantibodies / immunology*
  • Diabetes Mellitus, Type 1 / diagnosis*
  • Diabetes Mellitus, Type 1 / genetics
  • Diabetes Mellitus, Type 1 / immunology
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / genetics
  • Diabetes Mellitus, Type 2 / immunology
  • Diagnosis, Differential
  • Female
  • Glutamate Decarboxylase / immunology*
  • Hepatocyte Nuclear Factor 1-beta / genetics
  • Humans
  • Mutation
  • Pregnancy
  • Prognosis

Substances

  • Autoantibodies
  • HNF1B protein, human
  • Hepatocyte Nuclear Factor 1-beta
  • Glutamate Decarboxylase

Supplementary concepts

  • Mason-Type Diabetes