A versatile liquid-jet setup for the European XFEL

J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):339-345. doi: 10.1107/S1600577519000894. Epub 2019 Feb 22.

Abstract

The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as well as high-viscosity extruders and provides space and flexibility for other liquid injection devices and future upgrades. The liquid jets are confined in a differentially pumped catcher assembly and can be replaced within a couple of minutes through a load-lock. A two-microscope imaging system allows visual control of the jets from two perspectives.

Keywords: FEL physics; instrumentation; liquid jets; sample delivery.