Atrioventricular block can be used as a risk predictor of clinical atrial fibrillation

Clin Cardiol. 2019 Apr;42(4):452-458. doi: 10.1002/clc.23167. Epub 2019 Mar 18.

Abstract

Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia, with its incidence making up nearly one-third of all hospital admissions. Atrioventricular block (AVB) is a conduction abnormality along the atrioventricular node or the His-Purkinje system. The relationship between atrioventricular conduction block and AF is controversial.

Hypothesis: This study is designed to observe whether there is a correlation between AVB and AF, and which type of AVB has the most obvious correlation with AF.

Methods: This study retrospectively reviewed 1345 patients. We classified the AVB according to the AVB classification criteria. One hundred and two patients were excluded, and the final total sample size was 1243 patients, including 679 patients in the AF group (378, 55.7% males) and 564 patients in the non-AF group (287, 50.8% males). AF group and non-AF group were compared to observe the relationship between AVB and AF.

Results: The I AVB have a relative statistical risk of 1.927 (95% confidence interval [CI]: 1.160-3.203, P < 0.05) with the occurrence of AF. II AVB occupied the largest proportion, accounting for 67 cases (9.87%), and the statistical risk of II AVB in AF is 16.845 (95% CI: 6.099-46.524, P < 0.000). III AVB has a comparative statistical risk of 17.599 (95% CI: 4.212-73.541, P < 0.000).

Conclusions: The three types of AVB in the AF group were significantly higher than that in the non-AF group. II AVB has the highest incidence rate compared with other types of AVB in the AF group. AVB can be used as a risk factor for AF occurrence.

Keywords: I AVB; II AVB; III AVB; atrial fibrillation; risk indicator.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Atrial Fibrillation / epidemiology
  • Atrial Fibrillation / etiology*
  • Atrial Fibrillation / physiopathology
  • Atrioventricular Block / complications*
  • Atrioventricular Block / epidemiology
  • Atrioventricular Block / physiopathology
  • Atrioventricular Node / physiopathology*
  • China / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Risk Assessment / methods*
  • Time Factors
  • Young Adult