Treatment-refractory paraneoplastic opsoclonus-myoclonus syndrome in a patient with small-cell carcinoma of the lung

J Oncol Pharm Pract. 2020 Jan;26(1):209-211. doi: 10.1177/1078155219831366. Epub 2019 Feb 22.

Abstract

Opsoclonus-myoclonus syndrome is a rare disease and traditionally described as "dancing eyes, dancing feet syndrome." It is characterized by opsoclonus (oscillations of the eyes in either horizontally or vertically) and myoclonus (spontaneous jerky movements of the limbs and trunk). There are numerous etiological factors defined such as paraneoplastic, para-infectious, toxic-metabolic, and idiopathic causes. The experience of opsoclonus-myoclonus syndrome in adults is very limited. Here, we present a case of treatment-refractory paraneoplastic opsoclonus-myoclonus syndrome associated with small-cell carcinoma of the lung.

Keywords: Opsoclonus–myoclonus syndrome; paraneoplastic syndrome; small-cell lung cancer.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Lung Neoplasms / complications*
  • Male
  • Middle Aged
  • Opsoclonus-Myoclonus Syndrome / drug therapy*
  • Small Cell Lung Carcinoma / complications*