The challenge to the urology community is to reduce the risks of screening and treatment by reducing the number of men undergoing unnecessary biopsy and whole-gland curative treatment of low-risk disease. There is compelling evidence that focal ablation of prostate cancer is truly minimally invasive and offers major functional advantages over whole-gland treatment.
Keywords: Focal ablation; High-intensity focused ultrasound; Irreversible electroporation; Prostate cancer screening; Prostate cancer treatment; Vascular-targeted photodynamic therapy.