Predicting Early Response to Chemoradiotherapy for Uterine Cervical Cancer Using Intravoxel Incoherent Motion MR Imaging

Magn Reson Med Sci. 2019 Oct 15;18(4):293-298. doi: 10.2463/mrms.tn.2018-0138. Epub 2019 Feb 19.

Abstract

To assess if intravoxel incoherent motion (IVIM) imaging can be used to predict early response to chemoradiotherapy (CRT) in cervical cancer. IVIM imaging before and during CRT (at doses of 20 and 40 Gy) was performed in 17 patients with cervical squamous cell carcinoma. The percentage changes of IVIM parameters were significantly higher for complete remission (CR) than non-CR groups. IVIM may play a supplementary role for predicting early response to CRT in cervical cancer.

Keywords: chemoradiotherapy; intravoxel incoherent motion; treatment response; uterine cervical cancer.

MeSH terms

  • Chemoradiotherapy*
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Prognosis
  • Treatment Outcome
  • Uterine Cervical Neoplasms* / diagnostic imaging
  • Uterine Cervical Neoplasms* / therapy