In-situ modification of castor oil with divalent metal ions like Zn (II), Cu (II), Co (II) and Ba (II) and their comparative antioxidant study by in-vitro methods

Abstract

US Food and Drug Administration (FDA) permitted for direct addition of castor oil into food for human consumption and recently FDA approved castor oil as over-the-counter (OTC) for laxative drug. Castor oil (COL) is a vegetable oil and naturally polyol which is inexpensive, environmental friendly and a very valuable renewable resource. Metals are believed to influence antioxidant property of ligands. Metals copper, zinc, cobalt and barium were incorporated with castor oil and subsequently structures were established by FT-IR, UV-Visible, and ¹H NMR spectroscopic techniques. In vitro antioxidant activities of metal containing COL were determined by DPPH and superoxide scavenging methods and the results were compared with vitamin C. Enhanced antioxidant nature of metal containing castor oil was noticed and compared to virgin castor oil. This study reveals that synthesized metal containing-COL is a potential antioxidant material.

Keywords: Antioxidant; Castor Oil (COL); DPPH; Metal containing-COL, Cu, Co, Zn, Ba; Superoxide.