Polymeric hole-shaped polyhedral aggregates: Preparation, characterization, and antibacterial adhesion properties

J Colloid Interface Sci. 2019 Apr 1:541:461-469. doi: 10.1016/j.jcis.2019.01.112. Epub 2019 Jan 28.

Abstract

The diverse morphologies of aggregates formed by the self-assembly of block copolymers in selective solvents have attracted widespread attention, but the design of aggregate shapes is still limited owing to the thermodynamic favorability of sphere formation. In this paper, we report our discovery that polyhedral aggregates can be formed by the self-assembly of 1H,1H,2H,2H-perfluoro-1-dodecanol (PFD)-grafted amphiphilic polystyrene-b-poly(acrylic acid) (PS-b-PAA-g-PFD) copolymers in water at room temperature. It is determined that the crystallization of fluorocarbon side chains at the surface of PS-b-PAA-g-PFD aggregates induces the formation of a polyhedral shape. The morphology of aggregates can be controlled by the dialysis temperature, the grafting ratio of PFD in PS-b-PAA-g-PFD copolymers, and the initial copolymer concentration. The layers of polyhedral aggregates show excellent antibacterial adhesion properties. We anticipate that this method will expand the promise of self-assembly for the synthesis of a series of nonspherical micellar nanoparticles, which have promising applications in various fields.

Keywords: 1H, 1H, 2H, 2H-perfluoro-1-dodecanol; Block copolymers; Crystal; Poly(styrene-b-acrylic acid); Polyhedral aggregates.

MeSH terms

  • Acrylates / chemistry*
  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology*
  • Escherichia coli / drug effects*
  • Micelles*
  • Nanoparticles / administration & dosage
  • Nanoparticles / chemistry
  • Polymers / chemistry*
  • Polystyrenes / chemistry*
  • Staphylococcus aureus / drug effects*
  • Surface Properties

Substances

  • Acrylates
  • Anti-Bacterial Agents
  • Micelles
  • Polymers
  • Polystyrenes
  • poly(styrene-b-acrylic acid)