[The experimental clinical substantiation of treatment of patients with odontogenic phlegmon of maxillofacial area using Dаlargin in complex therapy]

Klin Lab Diagn. 2018;63(5):293-296. doi: 10.18821/0869-2084-2018-63-5-293-296.
[Article in Russian]

Abstract

The patients with odontogenic phlegmon of maxillofacial area suffer from immune depression at the surgical stage of treatment that can unfavorably affect their rehabilitation. The study analyzes possibility of application of medication Dalargin in complex treatment of patients during post-operation period. The experimental study established components of immune system affected by medication. Thereupon, Dalargin was applied in clinical practice of treatment of patients with course of disease of average severity. The study proved immunomodulatory characteristics of Dalargin effecting various fractions of sub-populations of lymphocytes and manifesting by way of decreasing of initially high indices and increasing of initially low indices that is of great importance during treatment of patients with odontogenic hormones, especially in case of severe course of disease.

Keywords: contaminated surgery; immunity; maxillofacial area; odontogenic phlegmon.

MeSH terms

  • Cellulitis / drug therapy*
  • Enkephalin, Leucine-2-Alanine / analogs & derivatives*
  • Enkephalin, Leucine-2-Alanine / therapeutic use
  • Humans

Substances

  • Enkephalin, Leucine-2-Alanine
  • enkephalin-Leu, Ala(2)-Arg(6)-